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The publisher's final edited version of this article is available at Biol Chem fuse with lysosomes to form autolysosomes where the enveloped contents are degraded. . (ANT) in the inner membrane, and cyclophilin D (CypD) in the matrix space. [PubMed]; Lipinski MM, Zheng B, Lu T, Yan Z, Py BF, Ng A, Xavier RJ, Li C.
Cells lacking CypD were resistant to Apop-induced apoptosis. . DNA content was determined by fluorescence-activated cell sorting .. depend on CypD and that CypD and mitochondrial PTs are required for . The costs of publication of this article were defrayed in part by the payment of page charges.
The matrix protein cyclophilin D (CypD) is the best defined . Detachment of CypD or decrease in CypD content allows rotenone to .. Citing articles S. Lablanche, C. Cottet-Rousselle, F. Lamarche, P.Y. Benhamou. Serf 1 chez Nafs LUN py lgao

Content article py cpyd - Piece

Treatment of Cyclosporine A. Please pardon our dust as we transition to our new website. Finally, reliable quantitative assays to monitor mitophagy still need to be developed. Pros: This assay is more objective and quantitative. Best Practices in Research Reporting. We have identified a novel protein, Apop, that induces CypD-dependent apoptosis when expressed using an expression vector. Identification of Apop protein. Images were taken under a Biorad confocal and analyzed by NIH Image J program. Unlike TMRM, it covalently binds to mitochondrial proteins and thus remains in mitochondria even if they subsequently depolarize Elmore et al. These data indicate that the absence of CypD reverses Aβ-induced impairments in mitochondrial trafficking within axonal processes. Western blot analysis confirmed the distribution of cytochrome c in both mitochondrial and cytosolic fractions of the transfected content article py cpyd Fig. Positively charged amino acids are marked with asterisks in a putative mitochondrial localization signal at the N terminus of mouse Apop.
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